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Certified Med Spas
Certified Med Spas

The AOD-9604 reading list

The original experiments, the human safety summary and the later reviews, gathered by subject.

Fat metabolism

The enzyme experiment and rat fat-tissue assay concern C-terminal growth-hormone fragments. The metabolic characterization of AOD9604, receptor-knockout experiment and fat-oxidation mouse study extend the biological record. Of these, I’d open the tissue assay first: the distinction between inhibiting fat formation and measuring fat breakdown is unusually clear there.

Human tolerability

The human safety report concerns oral AOD9604 in adults with obesity. The later sports-medicine review supplies a broader warning about the human safety evidence for unapproved peptides.

Identity and cartilage

The seized-preparations case report and urine-screening methods paper address analytical questions. The rabbit knee study concerns a different research direction, with a cartilage outcome in an animal model.

  1. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone ↗
  2. Metabolic actions of pituitary growth hormone. I. Inhibition of acetyl CoA carboxylase by human growth hormone and a carboxyl terminal part sequence acting through a second messenger ↗
  3. Antilipogenic action of synthetic C-terminal sequence 177-191 of human growth hormone ↗
  4. The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice ↗
  5. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment ↗
  6. Safety and Tolerability of the Hexadecapeptide AOD9604 in Humans ↗
  7. Identification and characterization of peptide drugs in unknown pharmaceutical preparations seized by the Belgian authorities: case report on AOD9604 ↗
  8. Simplifying and expanding the screening for peptides <2 kDa by direct urine injection, liquid chromatography, and ion mobility mass spectrometry ↗
  9. Effect of Intra-articular Injection of AOD9604 with or without Hyaluronic Acid in Rabbit Osteoarthritis Model ↗
  10. Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance ↗